Mirror duplication of chromosome 21 with complete phenotype of Down syndrome

Mirror duplication of chromosome 21 with complete phenotype of Down syndrome.

Partial trisomy of chromosome 21 without the Down syndrome phenotype.

Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan Department of Obstetrics and Gynecology, Kuo General Hospital, Tainan, Taiwan Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan *Correspondence to: Pao-Lin Kuo. E...

Chromosome Duplication (14q) and The Genotype Phenotype Correlation

Bioinformatics Investigation and Contribution of Other Chromosomes Besides Chromosome 21 in the Risk of Down Syndrome Development

Introduction: Down syndrome as a genetic disorder is a popular research topic in molecular studies. One way to study Down syndrome is via bioinformatics.  Methods: In this study, a gene expression profile from a microarray study was selected for more investigation. Results: The study of Down syndrome patients shows specific genes with differential expression and network centrality properties....

Molecular structure of the number 21 chromosome and Down syndrome.

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